The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

Brock Purdy may have cost himself some serious money this season. He wasn't bad, but he wasn't good, either. He was ...

DFS millionaire Mike McClure shares his top daily Fantasy football picks for San Francisco 49ers vs. Detroit lions on MNF ...

Talent-wise, the Lions' current unit is up there with some of the best offenses in NFL history, a list that includes the ...

Monday night’s loss ensured the 49ers stayed at the No. 11 pick with one week to go.

It's the Detroit Lions vs San Francisco 49ers on Monady Night Football in Week 17 of the 2024 NFL season. Here's how to watch ...

The San Francisco 49ers missed the playoffs entirely after making it to the Super Bowl last season. They will have some big questions to answer this offseason as they turn their attention to free ...

Former 49ers GM Trent Baalke can't escape the fan protests as fans flew a banner calling for him to get fired in Jacksonville ...

Here's when the San Francisco 49ers and the Arizona Cardinals will play their Week 18 game at State Farm Stadium.

The end of Brock Purdy's third NFL season is nearing and the final year of his rookie contract with the San Francisco 49ers ...