The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

Brock Purdy may have cost himself some serious money this season. He wasn't bad, but he wasn't good, either. He was ...

DFS millionaire Mike McClure shares his top daily Fantasy football picks for San Francisco 49ers vs. Detroit lions on MNF ...

Monday night’s loss ensured the 49ers stayed at the No. 11 pick with one week to go.

The San Francisco 49ers missed the playoffs entirely after making it to the Super Bowl last season. They will have some big questions to answer this offseason as they turn their attention to free ...

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers ...

The Detroit Lions offensive foursome of Gibbs, Montgomery, St. Brown and Williams makes NFL season history in win over 49ers ...

It's the Detroit Lions vs San Francisco 49ers on Monady Night Football in Week 17 of the 2024 NFL season. Here's how to watch ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted ...